Effect of thyroid peroxidase antibodies on thyroid-stimulating hormone reference limits in a primarily Latina population

Thyroid peroxidase antibodies, levels of thyroid stimulating hormone and development of hypothyroidism in euthyroid subjects.

OBJECTIVE Thyroid peroxidase antibodies (TPOAbs) have been found to be related to the levels of thyroid stimulating hormone (TSH) and to predict future development of thyroid failure in selected populations. We investigated these relations in a euthyroid general population. DESIGN Cross-sectional investigation of the relationship of TPOAbs and levels of TSH in euthyroid subjects. Prospective ...

Thyroid Stimulating Hormone Thyroid Stimulating Hormone

Should we really determine a reference population for the definition of thyroid-stimulating hormone reference interval?

Antithyroid peroxidase antibodies in patients with high normal range thyroid stimulating hormone.

BACKGROUND AND OBJECTIVES Hypothyroidism is linked to heart disease and decreased quality of life. Since screening guidelines for the general population are controversial, and physicians use clinical judgment in deciding to order thyroid stimulating hormone (TSH), high-normal levels of TSH pose a dilemma. This study's objective was to compare rates of positive anti-thyroid peroxidase antibodies...

Thyroid Stimulating Hormone Receptor

Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by sev...